A Bio-Mimetic Approach: Non-adverse Effects of Zinc Oxide Nanoparticles with Probiotic Isolate (Lactiplantibacillus plantarum)

Green nanotechnology utilises biological systems to produce nanoparticles, offering environmentally friendly and sustainable alternatives to traditional chemical methods.

Biosynthesis of zinc oxide nanoparticles (ZnO NPs) using novel probiotic bacteria from the gut of the snail Pila globosa-derived probiotics (Lactiplantibacillus plantarum)-has promising applications in the development of health-related feed supplements. ZnO:LP NPs represent a significant advancement in the biomimetic approach for enhancing biocompatibility, structural uniformity, and antimicrobial effectiveness.

Characterization of the synthesised nanoparticles, conducted using techniques such as Ultraviolet-Visible-Near Infrared (UV-Vis-NIR) spectroscopy, X-ray diffraction (XRD), Fourier Transform Infrared Spectroscopy (FTIR), Scanning Electron Microscopy (SEM), and Transmission Electron Microscopy (TEM), confirmed the successful formation of a hexagonal wurtzite structure. Biological assays were performed to investigate the synthesized nanoparticles, revealing significant antibacterial and cytotoxic activities.

This research highlights the promising applications of probiotic nanoparticles.

This research highlights the potential of probiotic-based nanoparticles for the development of comprehensive feed supplements with nutraceutical and nutri-biotechnological applications, as well as their implications for the food and healthcare industries.